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药理学研究 (2023年第190卷)

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【杂志介绍】《Pharmacological Research》主要发表生物医学领域的前沿文章,涵盖推动药理学领域向前发展的广泛主题。为跨学科专家提供了一个快速交换现代健康科学信息的平台。

April 2023 Volume1 90 (2023年4月第190卷)
https://www.sciencedirect.com/journal/pharmacological-research/vol/190/suppl/C

      Review Articles(综述文章
      1. 增殖性视网膜病变中的β3肾上腺素受体:“灰姑娘”走出家族阴影
    (The β3 adrenoceptor in proliferative retinopathies: “Cinderella” steps out of its family shadow)
      作者Maurizio Cammalleri (Department of Biology, University of Pisa, Italy)

      2. 烟碱型乙酰胆碱受体-脂质界面的结构和功能相遇
    (Structure and function meet at the nicotinic acetylcholine receptor-lipid interface)
      作者:Francisco J. Barrantes (Laboratory of Molecular Neurobiology, Biomedical Research Institute, Faculty of Medical Sciences, Pontifical Catholic University of Argentina (UCA)-Argentine Scientific & Technol. Argentina)

      3. 理解缰核:调节情绪和动机的回路中的一个主要节点
    (Understanding the habenula: A major node in circuits regulating emotion and motivation)
      作者:Jessica L. Ables, Inés Ibañez–Tallon* (sychiatry Department, Icahn School of Medicine at Mount Sinai, USA; he Laboratory of Molecular Biology, The Rockefeller University, USA)

      4. α7烟碱乙酰胆碱受体的沉默激动剂
    (Silent agonists for α7 nicotinic acetylcholine receptors)
      作者Roger L. Papke (Department of Pharmacology and Therapeutics, University of Florida, USA)

      5. α9α10乙酰胆碱受体:一种非神经元烟碱受体
    (The α9α10 acetylcholine receptor: A non-neuronal nicotinic receptor)
      作者Ana Belén Elgoyhen (Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres" (INGEBI),  Argentina)

      6. 癌症中miRNAs对HMGA2的调节:影响癌症特征和治疗反应
    (HMGA2 regulation by miRNAs in cancer: Affecting cancer hallmarks and therapy response)
      作者:Mehrdad Hashemi, Shokooh Salimimoghadam* (Farhikhtegan Medical Convergence Sciences Research Center, Farhikhtegan Hospital Tehran Medical Sciences, Islamic Azad University, Iran; Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Iran)

      7. 成人血液系统恶性肿瘤患者CAR-T细胞治疗后晚期复发:来自系统综述和个体数据Meta分析的明确证据
    (Late relapse after CAR-T cell therapy for adult patients with hematologic malignancies: A definite evidence from systematic review and meta-analysis on individual data)
      作者:Alessia Zinzi, Mario Gaio, Concetta Rafaniello* (Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, Italy)

      8. nAChRs与其他离子型和代谢型神经递质受体之间的中枢神经系统相互作用和串扰
    (Central nervous system interaction and crosstalk between nAChRs and other ionotropic and metabotropic neurotransmitter receptors)
      作者:Federica Bono, Chiara Fiorentini, Massimo Grilli* (Division of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia,  Italy; Department of Pharmacy, University of Genova, Italy)

      9. 尼古丁对发育中的大脑的作用
    (Nicotine on the developing brain)
      作者:Emily M. Castro, Frances M. Leslie* (Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University of California, USA)

      10. 烟碱乙酰胆碱受体:治疗疼痛和炎症的新型配体的治疗靶点
    (Nicotinic acetylcholine receptors: Therapeutic targets for novel ligands to treat pain and inflammation)
      作者Arik J. Hone (School of Biological Sciences University of Utah, USA)

      11. 烟碱受体在饮酒中的作用
    (The role of nicotinic receptors in alcohol consumption)
      作者Helen M. Kamens (Department of Biobehavioral Health, The Pennsylvania State University, USA)

      12. 翻译后修饰对烟碱型乙酰胆碱受体的调节
    (Regulation of nicotinic acetylcholine receptors by post-translational modifications)
      作者:Juan Facundo Chrestia, Cecilia Bouzat* (Instituto de Investigaciones Bioquímicas de Bahía Blanca, Argentina)

      13. IUPHAR——受邀评审——伊博甘——当前迷幻疗法复兴中的遗产
    (IUPHAR – invited review - Ibogaine – A legacy within the current renaissance of psychedelic therapy)
      作者:Deborah C. Mash (University of Miami Miller School of Medicine, Depts.)

      Research article研究文章
      1. eATP与自身免疫性糖尿病
    (eATP and autoimmune diabetes)
      作者:Cristian Loretelli, Paolo Fiorina* (International Center for T1D, Italy)

      2. 拓宽糖尿病肾病的机制、管理和治疗领域
    (Broadening horizons in mechanisms, management, and treatment of diabetic kidney disease)
      作者:Adriana Petrazzuolo, Francesca DAddio* (International Center for T1D, Italy)

      3. 首次使用自体细胞外囊泡治疗对常规治疗无反应的慢性静脉溃疡的试点病例对照干预研究
    (First pilot case-control interventional study using autologous extracellular vesicles to treat chronic venous ulcers unresponsive to conventional treatments)
      作者:Lorenzo Gibello, Giovanni Camussi*, Maria Felice Brizzi* (Division of Vascular Surgery, Department of Surgical Sciences, University of Turin, Italy; Department of Medical Sciences, University of Turin, Italy)

      4. 葛根抗性淀粉补充可通过正向微生物共生模式减轻缺血性卒中损伤
    (Gut microbiota-derived melatonin from Puerariae Lobatae Radix-resistant starch supplementation attenuates ischemic stroke injury via a positive microbial co-occurrence pattern)
      作者:Zhuoshi Lian, Ying Xu, Chan Wang, Zheng Cai* (NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, China)

      5. 一种MMP-9特异性中和抗体可减轻卒中小鼠的血脑屏障破坏,并降低卒中患者来源的MMP-9活性
    (An MMP-9 exclusive neutralizing antibody attenuates blood-brain barrier breakdown in mice with stroke and reduces stroke patient-derived MMP-9 activity)
      作者:Yabin Ji, Fuyou Guo* (Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, China; Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, China)

      6. 有机阴离子转运多肽2B1敲除和人源化小鼠;对胆红素和药物处理的见解
    (Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs)
      作者:Wenlong Li, Alfred H. Schinkel* (The Netherlands Cancer Institute, Division of Pharmacology, the Netherlands)

      7. 植物来源的外泌体样纳米颗粒在调节炎症反应和免疫系统微环境中的最新理解
    (Current understanding of plant-derived exosome-like nanoparticles in regulating the inflammatory response and immune system microenvironment)
      作者:Qiaoli Yi, Yuanliang Yan* (Department of Pharmacy, Xiangya Hospital, China), Zhijie Xu(Department of Pathology, Xiangya Hospital, China)

      8. CDK4/6的抑制通过DYRK1A/STAT3信号调节AD病理、神经炎症和认知功能
    (Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling)
      作者:Hyun-ju Lee, Hyang-Sook Hoe* (Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), the Republic of Korea)

      9. 双靶向ER和TrxR诱导乳腺癌症ICD的SERD-NHC-Au(I)复合物
    (SERD-NHC-Au(I) complexes for dual targeting ER and TrxR to induce ICD in breast cancer)
      作者:Yunlong Lu
1, Qianming Du2*, Wukun Liu1* (1. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, PR China; 2. General Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, PR China)

      10. 软肝颗粒增强恩替卡韦逆转慢性HBV感染患者晚期肝纤维化/早期肝硬化的疗效:一项多中心随机临床试验
    (Chinese herbal formula ruangan granule enhances the efficacy of entecavir to reverse advanced liver fibrosis/early cirrhosis in patients with chronic HBV infection: A multicenter, randomized clinical trial)
      作者:Yufeng Xing1, Weichao Zhong1, Deti Peng1, Hua Zhou2*, Guangdong Tong1* (1. Department of Hepatology, Shenzhen Traditional Chinese Medicine Hospital, China; 2. Guangdong Provincial Hospital of Chinese Medicine, China)

      11. α1-肾上腺素能受体配体通过干扰异聚体的形成抑制α1B/D-肾上腺素能受体的趋化因子受体异构伴侣
    (α1-adrenoceptor ligands inhibit chemokine receptor heteromerization partners of α1B/D-adrenoceptors via interference with heteromer formation)
      作者:Xianlong Gao, Matthias Majetschak* (Department of Surgery, Morsani College of Medicine, University of South Florida, USA)

      12. 靶向线粒体的新型罗尼达明衍生物通过阻断谷氨酰胺代谢消除癌症干细胞
    (A novel lonidamine derivative targeting mitochondria to eliminate cancer stem cells by blocking glutamine metabolism)
      作者:Qiang Wang, Shiyou Li, Zifu Li* (National Engineering Research Center for Nanomedicine, PR China)

      13. 降脂联合治疗:从预防到治疗动脉粥样硬化斑块
    (Lipid lowering combination therapy: From prevention to atherosclerosis plaque treatment)
      作者Lluís Masana (Unitat Medicina Vascular i Metabolism, Hospital Universitari Sant Joan, Spain)

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