脂毒性(Lipid Toxicity)
脂毒性(Lipid Toxicity):是指脂质在非脂肪组织中过多积聚,可能会导致细胞功能障碍或者死亡,此现象在糖尿病和心力衰竭等疾病的发生及发展过程中,直接影响胰岛β细胞、糖代谢途径,从而引起糖脂代谢紊乱、氧化应激、内质网应激及炎症反应。
参考文献
①《肾小管脂毒性在糖尿病肾病发病机制中的研究进展》
https://kns.cnki.net/kcms2/article/abstract?v=tJ8vF22QX-rY0gwrea5ktZZUTZJTRU55TsXJZlwzESTZwxOiGJeHZqCgeAuNkOxfOa__Rt0Yc-RyVGVs8xNPTZATpoJV-tIvEqujZFaMoV5dNcIA7jOCEdTtn7HTC4QQ4ubLgNhKHdo=&uniplatform=NZKPT&language=CHS
②《脂毒性在2型糖尿病发生发展中作用的研究进展》
https://kns.cnki.net/kcms2/article/abstract?v=tJ8vF22QX-ouYB8wuAxA5moia0jnFdOYjgo9A6YVO6QsyxEv-AFmFrSjYn1wsMRM8xrhFNs6pF6weciQiqe5DsMU1Od6nczkgxl22_Ns_oD2ceoj-cWkK6jKu3PDS9_0nG2F4x9k4Vi_IWe_CqQagw==&uniplatform=NZKPT&language=CHS
③《肾脏疾病中线粒体脂代谢与脂毒性的研究进展》
https://kns.cnki.net/kcms2/article/abstract?v=tJ8vF22QX-oFyHjrjUGz-HF-WM5XuXtb_6uZYiAFBJge2wAxIGBjJThtqbLI0XZGup_oA1SE36j0WRn1jwM3n6hB2H3BeMjMaClfr9m4txkP9SAa8QKIkRCWtn3J3dZ9TUrnkntG5qCs-RsewMeC_A==&uniplatform=NZKPT&language=CHS
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