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国际TOP10医学期刊药物治疗信息(2023年10月)

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一、临床肿瘤杂志 (2023年第73卷第5期)

September/October 2023 - Volume 73 - Issue 5 (2023年9/10月第73卷第5期)
https://acsjournals.onlinelibrary.wiley.com/toc/15424863/2023/73/5

二、柳叶刀 (2023年第402卷第10409-10412期)

(一)07 October 2023 - Volume 402 - Issue 10409 (2023年10月7日第402卷第10409期)
https://www.thelancet.com/journals/lancet/issue/vol402no10409/PIIS0140-6736(23)X0040-3

ARTICLES(文章)
1.NALIRIFOX与白蛋白结合型紫杉醇和吉西他滨在初治转移性胰腺导管腺癌患者中的比较(NAPOLI 3):一项随机、开放标签、3期试验
(NALIRIFOX versus nab-paclitaxel and gemcitabine in treatment-naive patients with metastatic pancreatic ductal adenocarcinoma (NAPOLI 3): a randomised, open-label, phase 3 trial)
作者:Zev A Wainberg* (Geffen School of Medicine, University of California Los Angeles, USA)

(二)14 October 2023 - Volume 402 - Issue 10410 (2023年10月14日第402卷第10410期)
https://www.thelancet.com/journals/lancet/issue/vol402no10410/PIIS0140-6736(23)X0041-5

CORRESPONDENCE(通信)
1.复杂性阑尾炎的抗生素疗程
(Duration of antibiotics in complicated appendicitis)
作者:Saif Ullah, Bing-Rong Liu* (Department of Gastroenterology, the First Affiliated Hospital of Zhengzhou University, China)
2.复杂性阑尾炎的抗生素疗程
(Duration of antibiotics in complicated appendicitis)
作者:Bing-Syuan Zeng, Chih-Wei Hsu* (Department of Internal Medicine, E-Da Cancer Hospital, I-Shou University, Taiwan, China; Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taiwan, China)
3.复杂性阑尾炎的抗生素疗程
(Duration of antibiotics in complicated appendicitis)
作者:Jiahao Meng, Shuguang Gao*
4.复杂性阑尾炎的抗生素疗程
(Duration of antibiotics in complicated appendicitis)
作者:Dimitrios Moris* (Department of Surgery, Duke University Medical Center, USA)
5.复杂性阑尾炎的抗生素疗程——作者回复
(Duration of antibiotics in complicated appendicitis– Authors' reply)
作者:Elisabeth M L de Wijkerslooth* (Department of Radiology, Maasstad Hospital, Netherlands)

(三)21 October 2023 - Volume 402 - Issue 10411 (2023年10月21日第402卷第10411期)
https://www.thelancet.com/journals/lancet/issue/vol402no10411/PIIS0140-6736(23)X0042-7

COMMENT(评论)
1.Sacituzumab govitecan 治疗 HR+ 和 HER2- 转移性乳腺癌:适用于所有人还是部分人?
(Sacituzumab govitecan in HR+ and HER2- metastatic breast cancer: for all or for some?)
作者:Sibylle Loibl* (German Breast Group, Forschungs, GermanyNeu-Isenburg and Centre for Haematology and Oncology Bethanien, Germany)
2.脑淀粉样血管病患者的抗凝治疗
(Anticoagulation in patients with cerebral amyloid angiopathy)
作者:Ashkan Shoamanesh* (Department of Medicine, Population Health Research Institute, McMaster University, Canada)
3.减少苯二氮䓬类受体激动剂用于治疗老年人失眠
(Deprescribing benzodiazepine receptor agonists for insomnia in older adults)
作者:Antoine Christiaens, Anne Spinewine* (Clinical Pharmacy, Louvain Drug Research Institute, Université catholique de Louvain, Belgium)
4.减少苯二氮䓬类受体激动剂用于治疗老年人失眠——作者回复
(Deprescribing benzodiazepine receptor agonists for insomnia in older adults– Authors' reply)
作者:Janet M Y Cheung, Michael Perlis* (School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Australia; Department of Psychiatry, University of Pennsylvania, USA)
ARTICLES(文章)
6.sacituzumab govitecan 在激素受体阳性和人表皮生长因子受体2阴性转移性乳腺癌(TROPiCS-02)中的总生存期:一项随机、开放标签、多中心、3期试验
(Overall survival with sacituzumab govitecan in hormone receptor-positive and human epidermal growth factor receptor 2-negative metastatic breast cancer (TROPiCS-02): a randomised, open-label, multicentre, phase 3 trial)
作者:Hope S Rugo* (Department of Medicine, University of California San Francisco, Helen Diller Family Comprehensive Cancer Center, USA)
7.Pegcetacoplan治疗年龄相关性黄斑变性继发地图样萎缩(OAKS和DERBY):两项多中心、随机、双盲、假对照、3期试验
(Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials)
作者:Jeffrey S Heier1, Eleonora M Lad2, Charles C Wykoff3* (1.Ophthalmic Consultants of Boston, USA; 2.Department of Ophthalmology, Duke University Medical Center, USA; 3.Retina Consultants of Texas, USA)
8.avacincaptad pegol治疗地图样萎缩(GATHER2)患者的疗效和安全性:一项随机、双盲、3期试验的12个月结果
(Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2): 12-month results from a randomised, double-masked, phase 3 trial)
作者:Arshad M Khanani* (Sierra Eye Associates, USA)

(四)28 October 2023 - Volume 402 - Issue 10412 (2023年10月28日第402卷第10412期)
https://www.thelancet.com/journals/lancet/issue/vol402no10412/PIIS0140-6736(23)X0043-9

ARTICLES(文章)
1.皮下注射佩索利单抗预防全身脓疱性银屑病(Effisayil 2)发作的疗效和安全性:一项国际、多中心、随机、安慰剂对照试验
(Efficacy and safety of subcutaneous spesolimab for the prevention of generalised pustular psoriasis flares (Effisayil 2): an international, multicentre, randomised, placebo-controlled trial)
作者:Akimichi Morita, Mark G Lebwohl* (Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Japan; Icahn School of Medicine at Mount Sinai, USA)

三、新英格兰医学杂志 (2023年10月第389卷第14-17期)

(一)5 October 2023 - Volume 389 - No 14 (2023年10月5日第389卷第14期)
https://www.nejm.org/toc/nejm/389/14

ORIGINAL ARTICLES(原创文章)
1.Sarilumab 治疗糖皮质激素减量期间风湿性多肌痛复发
(Sarilumab for Relapse of Polymyalgia Rheumatica during Glucocorticoid Taper)
作者:Robert F. Spiera* (Hospital for Special Surgery, Weill Cornell Medical College, USA)
2.艾氯胺酮鼻喷雾剂与喹硫平治疗难治性抑郁症的比较
(Esketamine Nasal Spray versus Quetiapine for Treatment-Resistant Depression)
作者:Andreas Reif* (Department of Psychiatry, Psychosomatic Medicine, and Psychotherapy, University Hospital Frankfurt–Goethe University, Germany)

CORRESPONDENCE(通信)
3.奥希替尼治疗切除的EGFR突变的NSCLC
(Osimertinib in Resected EGFR-Mutated NSCLC)

(二)12 October 2023 - Volume 389 - No 15 (2023年10月12日第389卷第15期)
https://www.nejm.org/toc/nejm/389/15

ORIGINAL ARTICLES(原创文章)
1.地塞米松辅助治疗HIV阳性成人结核性脑膜炎
(Adjunctive Dexamethasone for Tuberculous Meningitis in HIV-Positive Adults)
作者:Joseph Donovan* (Clinical Research Department, Rm. 359, London School of Hygiene and Tropical Medicine, UK)
2.头孢比罗酯钠治疗复杂性金黄色葡萄球菌菌血症
(Ceftobiprole for Treatment of Complicated Staphylococcus aureus Bacteremia)
作者:Thomas L. Holland* (Duke University Medical Center, USA)

CORRESPONDENCE(通信)
3.Zilebesiran 治疗高血压
(Zilebesiran for Hypertension)
4.美国针对Mpox的疫苗有效性
(Vaccine Effectiveness against Mpox in the United States)

(三)19 October 2023 - Volume 389 - No 16 (2023年10月19日第389卷第16期)
https://www.nejm.org/toc/nejm/389/16

ORIGINAL ARTICLES(原创文章)
1.恩扎卢胺改善生化复发性前列腺癌的预后
(Improved Outcomes with Enzalutamide in Biochemically Recurrent Prostate Cancer)
作者:Stephen J. Freedland, Neal D. Shor* (Samuel Oschin Comprehensive Cancer Institute, Cedars–Sinai Medical Center, Canada; Carolina Urologic Research Center, GenesisCare US, USA)
2.万古霉素和头孢唑林在关节置换术中预防性给药的试验
(Trial of Vancomycin and Cefazolin as Surgical Prophylaxis in Arthroplasty)
作者:Trisha N. Peel* (Department of Infectious Diseases, Monash University, Australia)

CORRESPONDENCE(通信)
3.无胰岛素史的2型糖尿病患者每周使用Icodec与每日使用甘精U100对比
(Weekly Icodec versus Daily Glargine U100 in Type 2 Diabetes without Previous Insulin)
4.非小细胞肺癌围手术期纳武利尤单抗与化疗
(Perioperative Nivolumab and Chemotherapy in Non–Small-Cell Lung Cancer)

(四)26 October 2023 - Volume 389 - No 17 (2023年10月26日第389卷第17期)
https://www.nejm.org/toc/nejm/389/17?query=main_nav_lg

ORIGINAL ARTICLES(原创文章)
1. Patisiran治疗转甲状腺素心脏淀粉样变性患者
(Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis)
作者:Mathew S. Maurer* (Department of Medicine, PH12 Stem Rm. 134, Columbia University Irving Medical Center, USA)
2.Nemolizumab治疗结节性痒疹患者的 3 期试验
(Phase 3 Trial of Nemolizumab in Patients with Prurigo Nodularis)
作者:Shawn G. Kwatra, Christophe Piketty* (Johns Hopkins Itch Center, Johns Hopkins University School of Medicine, USA; Galderma, Switzerland)

CORRESPONDENCE(通信)
3.三重激素受体激动剂Retatrutide治疗肥胖症
(Triple–Hormone-Receptor Agonist Retatrutide for Obesity)

四、美国医学会杂志 (2023年10月第330卷第13-16期)

(一)3 October 2023 -Volume 330 - No.13 (2023年10月3日第330卷第13期)
https://jamanetwork.com/journals/jama/issue/330/13

JAMA Insights(JAMA见解)
1.绝经期血管舒缩症状的非激素疗法
(Nonhormonal Therapies for Menopausal Vasomotor Symptoms)
作者:Jacob P. Christ (Department of Obstetrics and Gynecology, University of San Francisco, USA)

(二)10 October 2023 -Volume 330 - No.14 (2023年10月12日第330卷第14期)
https://jamanetwork.com/journals/jama/issue/330/14

Original Investigation(原始调查)
1.使用鼻用碘伏防菌剂与鼻用莫匹罗星抗生素在洗必泰冲洗中预防成人ICU感染的比较:一项随机临床试验
(Nasal Iodophor Antiseptic vs Nasal Mupirocin Antibiotic in the Setting of Chlorhexidine Bathing to Prevent Infections in Adult ICUs: A Randomized Clinical Trial)
作者:Susan S. Huang (University of California Irvine School of Medicine, USA)
2.Gefapixant 治疗难治性或不明原因慢性咳嗽的疗效和耐受性:系统综述和剂量-反应Meta分析
(Efficacy and Tolerability of Gefapixant for Treatment of Refractory or Unexplained Chronic Cough: A Systematic Review and Dose-Response Meta-Analysis)
作者:Elena Kum (Department of Health Research Methods, Evidence, and Impact, McMaster University, Canada)

Editorial(社论)
3.Gefapixant治疗难治性或不明原因的慢性咳嗽?
(Gefapixant for Refractory or Unexplained Chronic Cough?)
作者:Richard S. Irwin (Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Massachusetts Chan Medical School, USA)

JAMA Insights(JAMA见解)
4.多西环素暴露后的预防和性传播感染
(Doxycycline Postexposure Prophylaxis and Sexually Transmitted Infections)
作者:Kenneth H. Mayer (The Fenway Institute, Fenway Health, USA)

Medical News in Brief(医学新闻简讯)
5.司美格鲁肽与早期 1 型糖尿病患者的胰岛素需求减少相关
(Semaglutide Associated With Less Insulin Need in Early Type 1 Diabetes)
作者:Emily Harris
6.抗精神病药物可能被过度用于治疗痴呆症
(Antipsychotics Might Be Overprescribed for Dementia)
作者:Emily Harris
7.当止痛药与激素避孕药联合使用时会增加血栓形成风险
(Blot Clot Risk Higher When Pain Relievers Used With Hormonal Contraception)
作者:Emily Harris

(三)13 October 2023 -Volume 330 - No.15 (2023年10月13日第330卷第15期)
https://jamanetwork.com/journals/jama/issue/330/15

Original Investigation(原始调查)
1.Eplontersen 治疗遗传性转甲状腺素蛋白淀粉样变性伴多发性神经病
(Eplontersen for Hereditary Transthyretin Amyloidosis With Polyneuropathy)
作者:Teresa Coelho (Centro Hospitalar Universitário de Santo António, Portugal)

Medical News & Perspectives(医学观点和新闻)
2.谁应该-也能够-获得新的阿尔茨海默病药物Lecanemab?
(Who Should—and Can—Get Lecanemab, the New Alzheimer Disease Drug?)
作者:Rita Rubin

Comment & Response(评论与回应)
3.维生素K拮抗剂与血管内血栓切除术后的颅内出血
(Vitamin K Antagonists and Intracranial Hemorrhage After Endovascular Thrombectomy)
作者:Arosh S. Perera Molligoda Arachchige (IRCCS Humanitas Research Hospital, Humanitas University, Italy)
4.维生素K拮抗剂与血管内血栓切除术后的颅内出血——作者回复
(Vitamin K Antagonists and Intracranial Hemorrhage After Endovascular Thrombectomy—Reply)
作者:Brian Mac Grory (Duke Clinical Research Institute, Duke University School of Medicine, USA)

(四)24/31 October 2023 -Volume 330 - No.16 (2023年10月24/31日第330卷第16期)
https://jamanetwork.com/journals/jama/currentissue

Original Investigation(原始调查)
1.中药复方(通心络)及急性心肌梗死患者的临床结局:CTS-AMI 随机临床试验
(Traditional Chinese Medicine Compound (Tongxinluo) and Clinical Outcomes of Patients With Acute Myocardial Infarction:The CTS-AMI Randomized Clinical Trial)
作者:Yuejin Yang (State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, China)
2.妊娠糖尿病的早期二甲双胍治疗:一项随机临床试验
(Early Metformin in Gestational Diabetes:A Randomized Clinical Trial)
作者:Fidelma Dunne (College of Medicine Nursing and Health Sciences, University of Galway, Ireland)
3.头孢吡肟与哌拉西林-他唑巴坦在急性感染成人住院患者中的比较:ACORN随机临床试验
(Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection:The ACORN Randomized Clinical Trial)
作者:Edward T. Qian (Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, USA)

Editorial(社论)
4.脓毒症的经验性抗生素治疗急性肾损伤
(Acute Kidney Injury With Empirical Antibiotics for Sepsis)
作者:Steven Y. C. Tong (Peter Doherty Institute for Infection and Immunity, Victorian Infectious Diseases Service, Royal Melbourne Hospital, Australia)

Editor's Note(编者按)
5.治疗ST段抬高型心肌梗死的中药
(Traditional Chinese Medicine for ST-Segment Elevation Myocardial Infarction)
作者:Gregory Curfman

五、自然:药物发现综述 (2023年10月第22卷)

October 2023 - Volume 22 - Issue 10 (2023年10月第22卷第10期)
https://www.nature.com/nrd/volumes/22/issues/10

NEWS IN BRIEF(新闻简讯)
1.FDA批准首个用于产后抑郁的口服药物,但拒绝将其用于重度抑郁症
(FDA approves first oral drug for postpartum depression, but rejects it for major depressive disorder)
作者:Asher Mullard
2.FDA批准第二种RNA适配体
(FDA approves second RNA aptamer)
作者:Asher Mullard
3.FDA 批准首个 GPRC5D × CD3 靶向双特异性药物用于治疗多发性骨髓瘤
(FDA approves first GPRC5D × CD3-targeted bispecific for multiple myeloma)
作者:Asher Mullard

BIOBUSINESS BRIEFS(生物商业简报)
4.下一代CAR-T疗法的前景
(The next-generation CAR-T therapy landscape)
作者:Malvika Verma, John Wu* (Boston Consulting Group, Mountain View, USA; Boston Consulting Group, USA)

RESEARCH HIGHLIGHT(研究亮点)
5.微生物组筛选平台发现治疗细菌的药物
(Microbiome screening platform finds drugs for bugs)
作者:Katie Kingwell

Review Article(评论文章)
6.抗疟药物发现:进展和方法
(Antimalarial drug discovery: progress and approaches)
作者:Jair L. Siqueira-Neto, Elizabeth A. Winzeler* (University of California, USA)

六、自然:免疫学综述 (2023年10月第23卷第10期)

October 2023 - Volume 23 - Issue 10 (2023年10月第23卷第10期)
https://www.nature.com/nri/volumes/23/issues/10

In Brief(简讯)
1.干扰素ε在卵巢癌中的保护作用
(A protective role for interferon-ε in ovarian cancer)
作者:Yvonne Bordon

Review Article(评论文章)
2.评估通过疫苗产生的组织驻留记忆T细胞
(Assessing the generation of tissue resident memory T cells by vaccines)
作者:Elizabeth Rotrosen, Thomas S. Kupper* (Department of Dermatology, Brigham and Women’s Hospital, USA)
3.靶向IL-6反式信号转导:过去、现在和未来前景
(Targeting IL-6 trans-signalling: past, present and future prospects)
作者:Stefan Rose-John, Jürgen Scheller* (Biochemical Institute, Medical Faculty, Christian-Albrechts-University, Germany; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, Germany)

七、柳叶刀:呼吸医学 (2023年10月)

October 2023 - Volume 11 - Number 10 (2023年10月第11卷第10期)
https://www.thelancet.com/journals/lanres/issue/vol11no10/PIIS2213-2600(23)X0010-1

COMMENT(评论)
1.Nangibotide 用于感染性休克和 COVID-19 的精准免疫调节
(Nangibotide for precision immunomodulation in septic shock and COVID-19)
作者:Maniraj Neupane, Sameer S Kadri* (Critical Care Medicine Department, National Institutes of Health Clinical Center, USA)
2.贝福替尼——EGFR突变晚期NSCLC治疗的可行替代?
(Befotertinib—a viable alternative in EGFR-mutant advanced NSCLC?)
作者:Jessica Menis* (Medical Oncology Department, University and Hospital Trust of Verona, Italy)

ARTICLES(文章)
3.TREM-1 抑制剂nangibotide在感染性休克患者中的疗效、安全性和最佳生物标志物富集策略的前瞻性评估(ASTONISH):一项双盲、随机、对照、2b期试验
(Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial)
作者:Bruno François* (Réanimation Polyvalente—CHU Dupuytren, France)
4.贝福替尼(D-0316)与埃克替尼作为egfr突变的局部晚期或转移性非小细胞肺癌患者的一线治疗的比较:一项多中心、开放标签、随机3期研究
(Befotertinib (D-0316) versus icotinib as first-line therapy for patients with EGFR-mutated locally advanced or metastatic non-small-cell lung cancer: a multicentre, open-label, randomised phase 3 study)
作者:Shun Lu*, Jianying Zhou* (Department of Medical Oncology, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, China; Department of Respiratory Medicine, First Affiliated Hospital of Zhejiang University School of Medicine, China)

八、英国医学期刊 (2023年10月第383卷第8401-8404期)

(一)07 October 2023 - Volume 383 - Issue 8401 (2023年10月7日第383卷第8401期)
https://www.bmj.com/content/383/8401

(二)14 October 2023 - Volume 383 - Issue 8402 (2023年10月14日第383卷第8402期)
https://www.bmj.com/content/383/8402

Research(研究)
1.超声引导下皮质类固醇注射灌洗与有或无皮质类固醇注射的假灌洗,治疗肩关节钙化性腱鞘病:随机双盲多臂研究
(Ultrasound guided lavage with corticosteroid injection versus sham lavage with and without corticosteroid injection for calcific tendinopathy of shoulder: randomised double blinded multi-arm study)
作者:Stefan Moosmayer* (Department of Orthopedic Surgery, Martina Hansens Hospital, Norway)
2.钙化性肩袖肌腱病的灌洗治疗
(Lavage treatments for calcific rotator cuff tendinopathy)
作者:David M Robinson* (Department of Physical Medicine and Rehabilitation and Division of Sports Medicine, Mass General Brigham and Spaulding Rehabilitation Hospital/Harvard Medical School, USA)

(三)21 October 2023 - Volume 383 - Issue 8403 (2023年10月21日第383卷第8403期)
https://www.bmj.com/content/383/8403

Research(研究)
1.瑞舒伐他汀与阿托伐他汀治疗成人冠状动脉疾病:随机LODESTAR试验的二次分析
(Rosuvastatin versus atorvastatin treatment in adults with coronary artery disease: secondary analysis of the randomised LODESTAR trial)
作者:Yong-Joon Lee, Myeong-Ki Hong* (Division of Cardiology, Severance Hospital, Yonsei University College of Medicine, Korea)

(四)28 October 2023 - Volume 383 - Issue 8404 (2023年10月23日第383卷第8404期)
https://www.bmj.com/content/383/8404

九、自然:医学 (2023年10月第29卷第10期)

October 2023 - Volume 29 - Issue 10 (2023年10月第29卷第10期)
https://www.nature.com/nm/volumes/29/issues/10

Editorial(社论)
1.减轻体重
(Keeping the weight off)

NEWS(新闻)
2.结合mRNA和免疫疗法的个性化抗癌疫苗在黑色素瘤试验中的试验
(Personalized anti-cancer vaccine combining mRNA and immunotherapy tested in melanoma trial)
作者:Thiago Carvalho* (Lisbon, Portugal)
3.在诺和诺德有关Wegovy的新试验中发现减肥药可降低心血管疾病风险
(Weight-loss drug lowers cardiovascular disease risk in new trial of Novo Nordisk’s Wegovy)
作者:Ben Johnson

News & Views(新闻与观点)
4.肥胖症治疗的一场革命
(A revolution in obesity treatment)
作者:Ildiko Lingvay* (Division of Endocrinology, Department of Internal Medicine, The University of Texas Southwestern Medical Center, USA)
5.AI 支持的 2 型糖尿病胰岛素剂量
(AI-supported insulin dosing for type 2 diabetes)
作者:Georgia M. Davis* (Department of Medicine, Division of Endocrinology, Metabolism and Lipids, Emory University, USA)

Article(文章)
6.MDMA 辅助治疗中度至重度PTSD:一项随机、安慰剂对照的 3 期试验
(MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial)
作者:Jennifer M. Mitchell* (Neuroscape, Department of Neurology, University of California, USA)
7.轻度阿尔茨海默病中的衰老细胞清除疗法:一项1期可行性试验
(Senolytic therapy in mild Alzheimer’s disease: a phase 1 feasibility trial)
作者:Mitzi M. Gonzales* (Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, USA)
8.氯唑西林联合磷霉素与单独使用氯唑西林治疗甲氧西林敏感金黄色葡萄球菌菌血症的比较:一项随机试验
(Cloxacillin plus fosfomycin versus cloxacillin alone for methicillin-susceptible Staphylococcus aureus bacteremia: a randomized trial)
作者:Sara Grillo, Miquel Pujol* (Department of Infectious Diseases, Hospital Universitari de Bellvitge, Spain)
9.TLR9激动剂和广泛中和抗体对HIV-1持久性的影响:随机2a期TITAN试验
(Impact of a TLR9 agonist and broadly neutralizing antibodies on HIV-1 persistence: the randomized phase 2a TITAN trial)
作者:Jesper D. Gunst, Jesper F. Højen, Marie H. Pahus, Miriam Rosás-Umbert, Ole S. Søgaard* (Department of Clinical Medicine, Aarhus University, Denmark)
10.帕博利珠单抗治疗非小细胞肺癌后的ctDNA反应:2期适应性试验结果
(ctDNA response after pembrolizumab in non-small cell lung cancer: phase 2 adaptive trial results)
作者:Valsamo Anagnostou* (Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, USA)
11.Elranatamab治疗复发或难治性多发性骨髓瘤:MagnetisMM-1 1 期试验
(Elranatamab in relapsed or refractory multiple myeloma: the MagnetisMM-1 phase 1 trial)
作者:Nizar J. Bahlis* (Arnie Charbonneau Cancer Institute, University of Calgary, Canada)
12.Amivantamab联合lazertinib治疗奥希替尼复发性EGFR突变晚期非小细胞肺癌:1期试验
(Amivantamab plus lazertinib in osimertinib-relapsed EGFR-mutant advanced non-small cell lung cancer: a phase 1 trial)
作者:Byoung Chul Cho* (Division of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Korea)
13.H3K27M靶向疫苗治疗成人弥漫性中线胶质瘤
(A H3K27M-targeted vaccine in adults with diffuse midline glioma)
作者:Niklas Grassl, Michael Platten*, Katharina Sahm* (DKTK CCU Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Germany)
【注】H3K27M:组蛋白H3中赖氨酸27取代蛋氨酸
14.Garetosmab 治疗进展性骨化纤维发育不良:一项随机、双盲、安慰剂对照的 2 期试验
(Garetosmab in fibrodysplasia ossificans progressiva: a randomized, double-blind, placebo-controlled phase 2 trial)
作者:Maja Di Rocco, Scott J. Mellis* (Department of Pediatrics, Unit of Rare Diseases, IRCCS Istituto Giannina Gaslini, Italy; Regeneron Pharmaceuticals, USA)
15.利尿钠指导急性心力衰竭的利尿治疗:一项实用性随机试验
(Natriuresis-guided diuretic therapy in acute heart failure: a pragmatic randomized trial)
作者:Jozine M. ter Maaten* (Department of Cardiology, University Medical Center Groningen, University of Gronigen, the Netherlands)

十、世界精神病学 (2023年第22卷第3期)

(一)2023 - Volume 22 - Issue 3 (2023年第22卷第3期)
https://onlinelibrary.wiley.com/toc/20515545/2023/22/

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