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December 2023 - Volume 45 - Issue 6(2023年12月第45卷第6期)

      Grand Rounds(大查房)
      1. 头孢他啶血药浓度与神经毒性:在接受不同形式肾脏替代治疗的患者中监测治疗药物的重要性。一项大查房
      (Ceftazidime Plasma Concentrations and Neurotoxicity: The Importance of Therapeutic Drug Monitoring in Patients Undergoing Different Modalities of Renal Replacement Therapy. A Grand Round)
      作者:Roselle S. Robosa* (Department of Microbiology and Infectious Diseases, St Vincent's Hospital, Australia)  

      Review Article(综述文章)
      1. 与顺铂诱导耳毒性相关的遗传因素的系统评价综述:加拿大药物安全药物基因组学网络2022年更新
      (Systematic Critical Review of Genetic Factors Associated with Cisplatin-induced Ototoxicity: Canadian Pharmacogenomics Network for Drug Safety 2022 Update)
      作者:Scott Erika N. BMSc, Catrina M. Loucks* (BC Children's Hospital Research Institute, Canada)

      Original Article(原创文章)
      1. 人体汗液中不同药物类别的划分:汗液排出基本原理和治疗药物监测的意义
      (Diverse Drug Classes Partition into Human Sweat: Implications for Both Sweat Fundamentals and for Therapeutic Drug Monitoring)
      作者:Ruwe Theresa; Jason Heikenfeld* (Novel Device Laboratory, Biomedical Engineering Department, University of Cincinnati, Ohio)

      2. 利用PBPK系统的先验知识进一步了解谷浓度的常规临床数据:以他克莫司治疗慢性肾脏疾病为例
      (Using Prior Knowledge on Systems Through PBPK to Gain Further Insight into Routine Clinical Data on Trough Concentrations: The Case of Tacrolimus in Chronic Kidney Disease)
      作者:El-Khatee Eman , Amin Rostami-Hodjegan* (Certara UK Limited (Simcyp Division), UK)

      3. 长期服用利奈唑胺可增加成人耐药肺结核患者的药物暴露并降低药物清除和消除
      (Long-Term Intake of Linezolid Elevates Drug Exposure and Reduces Drug Clearance and Elimination in Adults With Drug-Resistant Pulmonary Tuberculosis)
      作者:Jeyakumar Shanmugam Murugaiha* (ICMR–National Institute for Research in Tuberculosis (NIRT), India)

      4. 白消安实验室间能力测试计划揭示了全球范围内药物定量和剂量建议的错误
      (Busulfan Interlaboratory Proficiency Testing Program Revealed Worldwide Errors in Drug Quantitation and Dose Recommendations)
      作者:Kweekel Dina M* (Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, The Netherlands)

      5. 在造血干细胞移植患者中,与标准的6点取样相比,使用输注结束和6小时浓度的有限取样策略高估了静脉内白消安清除率
      (Limited Sampling Strategy Using End of Infusion and Six-Hour Concentrations Overestimates Intravenous Busulfan Clearance Compared With Standard Six-Point Sampling in Hematopoietic Stem Cell Transplant Patients)
      作者:Salman Bushra Mustafa, Murtadha Al-Khabori* (Pharmacy Department, Sultan Qaboos Comprehensive Cancer Care & Research Centre, Oman, Department of Hematology, College of Medicine and Health Sciences, Sultan Qaboos University, Oman)

      6. 辅助阿片类药物戒断治疗的左美沙酮治疗药物监测:一份短通讯
      (Levomethadone Therapeutic Drug Monitoring to Aid Opioid Withdrawal Therapy: A Short Communication)
      作者:Pfeifer Philippe* (University Hospital of Psychiatry and Psychotherapy Bern, Switzerland) 

      7. 羟考酮、吗啡和芬太尼在慢性疼痛患者中的作用:剂量特异性浓度范围的建议
      (Oxycodone, Morphine, and Fentanyl in Patients With Chronic Pain: Proposal of Dose-Specific Concentration Ranges)
      作者:Thaulow, Cecilie Hassel* (Division of Laboratory Medicine, Department of Forensic Sciences, Oslo University Hospital, Oslo)

      8. 真实环境设定中替加环素在肝损伤患者中的药代动力学/药效学目标实现
      (Pharmacokinetic/Pharmacodynamic Target Attainment of Tigecycline in Patients with Hepatic Impairment in a Real-World Setting)
      作者:Yang Xiaoxuan, Hang Liu* (Department of Pharmacy, China Pharmaceutical University Nanjing Drum Tower Hospital, China; Department of Pharmacy, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, China)

      9. 接种SARS-CoV-2疫苗后精神药物血药水平的变化:一项双中心队列研究
      (Changes in Psychotropic Drug Blood Levels After SARS-CoV-2 Vaccination: A Two-Center Cohort Study)
      作者:Kuzin Maxim* (Clienia Schloessli, Private Psychiatric Hospital and Academic Teaching Hospital of the University of Zurich, Switzerland)

      10. 研究托吡酯在癫痫患者中的非参数模型群体药代动力学
      (Population Pharmacokinetics of Topiramate in Patients with Epilepsy Using Nonparametric Modeling)
      作者:Elewa Mandy* (Department of Pharmacology and Therapeutics, College of Pharmacy, Kuwait University, Kuwait)

      11. 袖状胃切除术和Roux-en-Y胃旁路手术对艾司西酞普兰药代动力学的影响:一项队列研究
      (Effects of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass on Escitalopram Pharmacokinetics: A Cohort Study)
      作者:Schoretsanitis Georgios* (The Zucker Hillside Hospital, Psychiatry Research, Northwell Health, USA)

      Short Communication(短通信)
      1. 口服液中锂离子浓度的快速检测
      (Rapid Detection of Lithium Concentrations in Oral Fluid)
      作者:Granger Douglas A.; Thomas Elizabeth A.* (Institute for Interdisciplinary Salivary Bioscience Research, University of California Irvine, USA)

      2. 人血浆中舒尼替尼和N -去乙基舒尼替尼的LC-MS/MS优化定量方法及其在治疗药物监测中的应用
      (An Optimized LC-MS/MS Method for Quantification of Sunitinib and N-Desethyl Sunitinib in Human Plasma and Its Application for Therapeutic Drug Monitoring)
      作者:Li Qiaoqiao, Chen Wanyi* (Department of Pharmacy, Chongqing University Cancer Hospital, China)

      3. 替莫唑胺在恶性胶质瘤血液透析患者中的药代动力学:一份短通讯
      (Pharmacokinetics of Temozolomide in a Patient With Glioblastoma Undergoing Hemodialysis: A Short Communication)
      作者:Tanaka Fumiaki, Irie Kei* (Department of Pharmacy, Kobe City Medical Center General Hospital, Japan)

      4. 高效液相色谱-串联质谱法检测白消安中PEG-400离子的抑制作用
      (PEG 400 Ion Suppression in Busulfan Detection by High-Performance Liquid Chromatography—Tandem Mass Spectrometry)
      作者:De Gregori Simona (Clinical and Experimental Pharmacokinetics Unit, Department of Diagnostic Medicine, Fondazione IRCCS Policlinico San Matteo, Italy)

      5. 2例接受体外膜肺氧合治疗的患儿的头孢曲松钠药代动力学和药效学
      (Ceftriaxone Pharmacokinetics and Pharmacodynamics in 2 Pediatric Patients on Extracorporeal Membrane Oxygenation Therapy)
      作者:Cervantes Francisco, Tang Girdwood, Sonya* (Department of Medical Education, University of Cincinnati College of Medicine, Cincinnati, Ohio. Arbough is now with the Department of Anesthesiology, University of Kentucky College of Medicine, Kentucky; Department of Pediatrics, University of Cincinnati College of Medicine, Ohio)

      6. 3-甲基甲卡西酮中毒:血药浓度与临床结果的差异—一份短通讯
      (3-Methylmethcathinone Intoxication: Discrepancies Between Blood Concentrations and Clinical Outcomes—A Short Communication)
      作者:Drevin Guillaume* (Service de Pharmacologie-Toxicologie et Pharmacovigilance, France)